Assessing Site Specificity of Osteoarthritic Gait Kinematics with Wearable Sensors and Their Association with Patient Reported Outcome Measures (PROMs): Knee versus Hip Osteoarthritis

There is a great need for quantitative outcomes reflecting the functional status in patients with knee or hip osteoarthritis (OA) to advance development and investigation of interventions OA. The purpose this study was determine if gait kinematics specific disease—i.e., versus OA—can be identified using wearable sensors statistical parametric mapping (SPM) whether disease-related deviations are associated patient reported outcome measures. 113 participants (N = 29 unilateral OA; N 30 54 age-matched asymptomatic persons) completed analysis Knee/Hip Osteoarthritis Outcome Score (KOOS/HOOS). Data were analyzed SPM. Knee differed between OA (up 14°, p < 0.001 8°, 0.003 kinematics), differences from controls more pronounced affected than unaffected leg patients. observed ankle, kinematic trajectories KOOS/HOOS both groups. Capturing wearables has large potential application as clinical trials monitoring treatment success cohorts representing major advancement research on musculoskeletal diseases.